Patients with ANCA-associated vasculitis admitted to the intensive care unit with acute vasculitis manifestations: a retrospective and comparative multicentric study.

ABSTRACT:

Purpose

Data for ANCA-associated vasculitis (AAV) patients requiring intensive care are scarce.

Methods

We included 97 consecutive patients with acute AAV manifestations (new onset or relapsing disease), admitted to 18 intensive care units (ICUs) over a 10-year period (2002-2012). A group of 95 consecutive AAV patients with new onset or relapsing disease, admitted to two nephrology departments with acute vasculitis manifestations, constituted the control group.

Results

In the ICU group, patients predominantly showed granulomatosis with polyangiitis and proteinase-3 ANCAs. Compared with the non-ICU group, the ICU group showed comparable Birmingham vasculitis activity score and a higher frequency of heart, central nervous system and lungs involvements. Respiratory assis

SUBMITTER: Demiselle J 

PROVIDER: S-EPMC5382116 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature