Association between fibromyalgia syndrome and peptic ulcer disease development.

ABSTRACT:

Purpose

The correlation of fibromyalgia syndrome (FMS) with peptic ulcer disease (PUD) is unclear. We therefore conducted a cohort study to investigate whether FMS is correlated with an increased risk of PUD.

Methods

In this study, we established an FMS cohort comprising 26068 patients aged more than 20 years who were diagnosed with FMS from 2000 to 2011. Furthermore, we established a control cohort by randomly choosing 104269 people without FMS who were matched to the FMS patients by gender, age, and index year. All patients were free of PUD at the baseline. Cox proportional hazard regressions were performed to compute the hazard ratio of PUD after adjustment for demographic characteristics and comorbidities.

Results

The prevalence of comorbidities was significantly

SUBMITTER: Wang KA 

PROVIDER: S-EPMC5383298 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature