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Whole-Genome Sequences of Burkholderia pseudomallei Isolates Exhibiting Decreased Meropenem Susceptibility.

ABSTRACT: We report here paired isogenic Burkholderia pseudomallei genomes obtained from three patients receiving intravenous meropenem for melioidosis treatment, with post-meropenem isolates developing decreased susceptibility. Two genomes were finished, and four were drafted to improved high-quality standard. These genomes will be used to identify meropenem resistance mechanisms in B. pseudomallei.

SUBMITTER: Price EP 

PROVIDER: S-EPMC5383878 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature

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Whole-Genome Sequences of <i>Burkholderia pseudomallei</i> Isolates Exhibiting Decreased Meropenem Susceptibility.

Price Erin P EP   Smith Melissa Laird ML   Paxinos Ellen E EE   Tallon Luke J LJ   Sadzewicz Lisa L   Sengamalay Naomi N   Baird Robert W RW   Currie Bart J BJ   Sarovich Derek S DS  

Genome announcements 20170406 14

We report here paired isogenic <i>Burkholderia pseudomallei</i> genomes obtained from three patients receiving intravenous meropenem for melioidosis treatment, with post-meropenem isolates developing decreased susceptibility. Two genomes were finished, and four were drafted to improved high-quality standard. These genomes will be used to identify meropenem resistance mechanisms in <i>B. pseudomallei</i>. ...[more]

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