Genome Sequence of the Fungal Strain 14919 Producing 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Inhibitor FR901512.

ABSTRACT: Fungal strain 14919 was originally isolated from a soil sample collected at Mt. Kiyosumi, Chiba Prefecture, Japan. It produces FR901512, a potent and strong 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor. The genome sequence of fungal strain 14919 was determined and annotated to improve the productivity of FR901512.

SUBMITTER: Itoh H 

PROVIDER: S-EPMC5383895 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature