Photodynamic therapy with polyhematoporphyrin for malignant biliary obstruction: A nationwide retrospective study of 150 consecutive applications.

ABSTRACT:

Background

Photodynamic therapy (PDT) is a palliative treatment for malignant biliary obstruction.

Objective

The objective of this article is to assess the feasibility and safety of this technique.

Methods

In this nationwide, retrospective study of prospectively collected clinical data, all patients treated with PDT using polyhematoporphyrin in Austria from March 2004 to May 2013 were included. Feasibility, adverse events, stent patency and mortality rates were investigated.

Results

Eighty-eight patients (54 male, 34 female, median age 69 years) underwent 150 PDT procedures at seven Austrian referral centers for biliary endoscopy. The predominant underlying disease was Klatskin tumor (79/88). All PDT procedures were feasible without technical issues. Cholangiti

SUBMITTER: Dolak W 

PROVIDER: S-EPMC5384559 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature