Clinical decision tool for CRT-P vs. CRT-D implantation: Findings from PROSE-ICD.

ABSTRACT:

Background

Cardiac resynchronization therapy (CRT) devices reduce mortality through pacing-induced cardiac resynchronization and implantable cardioverter defibrillator (ICD) therapy for ventricular arrhythmias (VAs). Whether certain factors can predict if patients will benefit more from implantation of CRT pacemakers (CRT-P) or CRT defibrillators (CRT-D) remains unclear.

Methods and results

We followed 305 primary prevention CRT-D recipients for the two primary outcomes of HF hospitalization and ICD therapy for VAs. Serum biomarkers, electrocardiographic and clinical variables were collected prior to implant. Multivariable analysis using Cox-proportional hazards model was used to fit the final models. Among 282 patients with follow-up outcome data, 75 (26.6%) were hospitaliz

SUBMITTER: Nauffal V 

PROVIDER: S-EPMC5384669 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature