Epidemiology of venous thromboembolism in the Framingham Heart Study.

ABSTRACT:

Background

Reports of the crude incidence of venous thromboembolism (VTE) in Western countries vary widely. Data regarding risk factors, incidence and recurrence of VTE from deeply-phenotyped community-based cohort studies are needed.

Objectives

To study the incidence, associated mortality, and predisposing factors of VTE in the prospective, longitudinal community-based Framingham Heart Study.

Patients/methods

The study sample consisted of the Framingham Heart Study Original, Offspring, Third Generation, and Omni cohorts (N=9754). Incidence rates (IR) were standardized to the 2000 US population. Cox proportional hazards regression models were used to study risk factor associations.

Results

During 1995-2014 (total follow-up time 104,091 person-years [median 9.8

SUBMITTER: Puurunen MK 

PROVIDER: S-EPMC5385100 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature