Dissociated patterns of anti-correlations with dorsal and ventral default-mode networks at rest.

ABSTRACT: Previous studies of resting state functional connectivity have demonstrated that the default-mode network (DMN) is negatively correlated with a set of brain regions commonly activated during goal-directed tasks. However, the location and extent of anti-correlations are inconsistent across different studies, which has been posited to result largely from differences in whether or not global signal regression (GSR) was applied as a pre-processing step. Notably, coordinates of seed regions-of-interest defined within the posterior cingulate cortex (PCC)/precuneus, an area often employed to study functional connectivity of the DMN, have been inconsistent across studies. Taken together with recent observations that the DMN contains functionally heterogeneous subdivisions, it is presently unclear

SUBMITTER: Chen JE 

PROVIDER: S-EPMC5385153 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature