Genomic and molecular characterization of a novel quorum sensing molecule in Bacillus licheniformis.

ABSTRACT: Quorum sensing molecules (QSMs) are involved in the regulation of complicated processes helping bacterial populations respond to changes in their cell-density. Although the QS gene cluster (comQXPA) has been identified in the genome sequence of some bacilli, the QS system B. licheniformis has not been investigated in detail, and its QSM (ComX pheromone) has not been identified. Given the importance of this antagonistic bacterium as an industrial workhorse, this study was aimed to elucidate B. licheniformis NCIMB-8874 QS. The results obtained from bioinformatics studies on the whole genome sequence of this strain confirmed the presence of essential quorum sensing-related genes. Although polymorphism was verified in three proteins of this cluster, ComQ, precursor-ComX and ComP, the transcrip

SUBMITTER: Esmaeilishirazifard E 

PROVIDER: S-EPMC5385187 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature