Dataset Information

Cross-sectional associations of impaired glucose metabolism measures with bleeding on probing and periodontitis.

ABSTRACT:

Aim

This study assessed the associations of pre-diabetes and insulin resistance with bleeding on probing (BOP) and periodontitis among adults.

Materials and methods

We included 1191 Hispanic adults aged 40-65 years, free of diabetes, enrolled in San Juan Overweight Adults Longitudinal Study. Pre-diabetes was defined as impaired fasting glucose (IFG), impaired glucose tolerance (IGT), or impaired glycated haemoglobin. Impaired one-hour plasma glucose (1hPG) was defined as levels >155 mg/dl. Insulin resistance was defined using the study population-specific 75th percentile (HOMA-IR ≥ 3.13). High BOP was defined as percentage of teeth with bleeding ≥30%. Periodontitis was defined according to the CDC/AAP definition.

Results

After multivariable adjustment for age, gender, education, smoking status, alcohol consumption, physical activity, obesity, HDL-C, and plaque index, pre-diabetes with and without 1hPG, IFG, impaired 1hPG, IGT, and HOMA-IR were significantly associated with high BOP; pre-diabetes, IFG, and impaired 1hPG were significantly associated with severe periodontitis. Most of these associations remained significant when the analyses were restricted to non-smokers.

Conclusions

This study suggests associations between pre-diabetes and insulin resistance with BOP and periodontitis. Given the high prevalence of impaired glucose metabolism and periodontitis, the assessment of the temporal sequence of these associations is of utmost importance.

SUBMITTER: Perez CM

PROVIDER: S-EPMC5385925 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature

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Publications

Cross-sectional associations of impaired glucose metabolism measures with bleeding on probing and periodontitis.

Pérez Cynthia M CM Muñoz Francisco F Andriankaja Oelisoa M OM Ritchie Christine S CS Martínez Sasha S Vergara José J Vivaldi José J López Lydia L Campos Maribel M Joshipura Kaumudi J KJ

Journal of clinical periodontology 20170113 2

<h4>Aim</h4>This study assessed the associations of pre-diabetes and insulin resistance with bleeding on probing (BOP) and periodontitis among adults.<h4>Materials and methods</h4>We included 1191 Hispanic adults aged 40-65 years, free of diabetes, enrolled in San Juan Overweight Adults Longitudinal Study. Pre-diabetes was defined as impaired fasting glucose (IFG), impaired glucose tolerance (IGT), or impaired glycated haemoglobin. Impaired one-hour plasma glucose (1hPG) was defined as levels >1 ...[more]

PMID: 27978601

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Dataset Information

Cross-sectional associations of impaired glucose metabolism measures with bleeding on probing and periodontitis.

Aim

Materials and methods

Results

Conclusions

Publications

Cross-sectional associations of impaired glucose metabolism measures with bleeding on probing and periodontitis.

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