Associations of fat and muscle tissue with cognitive status in older adults: the AGES-Reykjavik Study.

ABSTRACT:

Background/objective

studies on the association of dementia with specific body composition (BC) components are scarce. Our aim was to investigate associations of BC measures with different levels of cognitive function in late-life.

Methods

we studied 5,169 participants (mean age 76 years, 42.9% men) in the AGES-Reykjavik Study of whom 485 (9.4%) were diagnosed with mild cognitive impairment (MCI) and 307 (5.9%) with dementia. Visceral fat, abdominal and thigh subcutaneous fat, and thigh muscle were assessed by computed tomography. MCI and dementia were based on clinical assessment and a consensus meeting; those without MCI or dementia were categorised as normal. Multinomial regression models assessed the associations stratified by sex and in additional analyses by midlife bo

SUBMITTER: Spauwen PJ 

PROVIDER: S-EPMC5386007 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature