Comparative Transcriptomics of Malaria Mosquito Testes: Function, Evolution, and Linkage.

ABSTRACT: Testes-biased genes evolve rapidly and are important in the establishment, solidification, and maintenance of reproductive isolation between incipient species. The Anopheles gambiae complex, a group of at least eight isomorphic mosquito species endemic to Sub-Saharan Africa, is an excellent system to explore the evolution of testes-biased genes. Within this group, the testes are an important tissue in the diversification process because hybridization between species results in sterile hybrid males, but fully fertile females. We conducted RNA sequencing of A. gambiae and A. merus carcass and testes to explore tissue- and species-specific patterns of gene expression. Our data provides support for transcriptional repression of X-linked genes in the male germline, which li

SUBMITTER: Cassone BJ 

PROVIDER: S-EPMC5386861 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature