Unstable Inheritance of 45S rRNA Genes in <i>Arabidopsis thaliana</i>.

ABSTRACT: The considerable genome size variation in Arabidopsis thaliana has been shown largely to be due to copy number variation (CNV) in 45S ribosomal RNA (rRNA) genes. Surprisingly, attempts to map this variation by means of genome-wide association studies (GWAS) failed to identify either of the two likely sources, namely the nucleolus organizer regions (NORs). Instead, GWAS implicated a trans-acting locus, as if rRNA gene CNV was a phenotype rather than a genotype. To explain these results, we investigated the inheritance and stability of rRNA gene copy number using the variety of genetic resources available in A. thaliana - F2 crosses, recombinant inbred lines, the multiparent advanced-generation inter-cross population, and mutation accumulation lines. Our results clearly

SUBMITTER: Rabanal FA 

PROVIDER: S-EPMC5386868 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature