Biomarkers of systemic lupus erythematosus identified using mass spectrometry-based proteomics: a systematic review.

ABSTRACT: Advances in mass spectrometry technologies have created new opportunities for discovering novel protein biomarkers in systemic lupus erythematosus (SLE). We performed a systematic review of published reports on proteomic biomarkers identified in SLE patients using mass spectrometry-based proteomics and highlight their potential disease association and clinical utility. Two electronic databases, MEDLINE and EMBASE, were systematically searched up to July 2015. The methodological quality of studies included in the review was performed according to Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines. Twenty-five studies were included in the review, identifying 241 SLE candidate proteomic biomarkers related to various aspects of the disease including disease diagnosis

SUBMITTER: Nicolaou O 

PROVIDER: S-EPMC5387176 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature