Association between rhinovirus wheezing illness and the development of childhood asthma: a meta-analysis.

ABSTRACT:

Objective

The relation between early-life rhinovirus (RV) wheezing illness and later onset of wheezing/asthma remains a subject of debate. Therefore, we conducted this meta-analysis to evaluate the association between RV wheezing illness in the first 3 years of life and the subsequent development of wheezing/asthma.

Design

Systematic review and meta-analysis.

Methods

The PubMed, EMBASE, Web of Science, Chinese National Knowledge Infrastructure (CNKI) and Wanfang databases were systematically searched for studies published between 1988 and February 2017, and additional studies were found by searching reference lists of relevant articles. 2 reviewers independently extracted data and assessed the quality of each study. Results were pooled using fixed-effect models or ran

SUBMITTER: Liu L 

PROVIDER: S-EPMC5387933 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature