Glucose challenge test screening for prediabetes and early diabetes.

ABSTRACT:

Aims

To test the hypothesis that a 50-g oral glucose challenge test with 1-h glucose measurement would have superior performance compared with other opportunistic screening methods.

Methods

In this prospective study in a Veterans Health Administration primary care clinic, the following test performances, measured by area under receiver-operating characteristic curves, were compared: 50-g oral glucose challenge test; random glucose; and HbA_1c level, using a 75-g oral glucose tolerance test as the 'gold standard'.

Results

The study population was comprised of 1535 people (mean age 56 years, BMI 30.3 kg/m² , 94% men, 74% black). By oral glucose tolerance test criteria, diabetes was present in 10% and high-risk prediabetes was present in 22% of parti

SUBMITTER: Jackson SL 

PROVIDER: S-EPMC5388592 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature