Predominance and association risk of Blastocystis hominis subtype I in colorectal cancer: a case control study.

ABSTRACT:

Background

Blastocystis, a genetically diverse intestinal parasite with controversial pathogenic potential, has increasingly been incriminated for diarrheal illness in immunocompromised individuals including colorectal cancer (CRC) patients. The aim of the current study was to assess the possible association between Blastocystis infection and CRC condition in Makkah, Saudi Arabia (KSA).

Methods

Stool samples were collected from 80 non-cancer (NC) and 138 cancer subjects including 74 CRC patients and 64 patients with other cancers outside gastrointestinal tract (COGT). Molecularly confirmed Blastocystis isolates were genetically grouped and subtyped using multiplex polymerase chain reaction with restriction fragment length polymorphism (PCR-RFLP) and sequ

SUBMITTER: Mohamed AM 

PROVIDER: S-EPMC5389010 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature