Characterization of genome-wide segmental duplications reveals a common genomic feature of association with immunity among domestic animals.

ABSTRACT:

Background

Segmental duplications (SDs) commonly exist in plant and animal genomes, playing crucial roles in genomic rearrangement, gene innovation and the formation of copy number variants. However, they have received little attention in most livestock species.

Results

Aiming at characterizing SDs across the genomes of diverse livestock species, we mapped genome-wide SDs of horse, rabbit, goat, sheep and chicken, and also enhanced the existing SD maps of cattle and pig genomes based on the most updated genome assemblies. We adopted two different detection strategies, whole genome analysis comparison and whole genome shotgun sequence detection, to pursue more convincing findings. Accordingly we identified SDs for each species with the length of from 21.7 Mb to 164.1 Mb, and

SUBMITTER: Feng X 

PROVIDER: S-EPMC5389087 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature