Estimating the standardized incidence ratio (SIR) with incomplete follow-up data.

ABSTRACT:

Background

A standard parameter to compare the disease incidence of a cohort relative to the population is the standardized incidence ratio (SIR). For statistical inference is commonly assumed that the denominator, the expected number of cases, is fixed. If a disease registry is available, incident cases can sometimes be identified by linkage with the registry, however, registries may not contain information on migration or death from other causes. A complete follow-up with a population registry may not be possible. In that case, end-of-follow-up date and therefore, exact person-years of observation are unknown.

Methods

We have developed a method to estimate the observation times and to derive the expected number of cases using population data on mortality and migration rate

SUBMITTER: Becher H 

PROVIDER: S-EPMC5389158 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature