Selective detection of Mg²⁺ ions via enhanced fluorescence emission using Au-DNA nanocomposites.

ABSTRACT: The biophysical properties of DNA-modified Au nanoparticles (AuNPs) have attracted a great deal of research interest for various applications in biosensing. AuNPs have strong binding capability to the phosphate and sugar groups in DNA, rendering unique physicochemical properties for detection of metal ions. The formation of Au-DNA nanocomposites is evident from the observed changes in the optical absorption, plasmon band, zeta potential, DLS particle size distribution, as well as TEM and AFM surface morphology analysis. Circular dichroism studies also revealed that DNA-functionalized AuNP binding caused a conformational change in the DNA structure. Due to the size and shape dependent plasmonic interactions of AuNPs (33-78 nm) with DNA, the resultant Au-DNA nanocomposites (NCs) exhibit supe

SUBMITTER: Basu T 

PROVIDER: S-EPMC5389202 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature