No preemptive analgesic effect of preoperative ketorolac administration following total abdominal hysterectomy: A randomized study.

ABSTRACT:

Background

Experimental models using short-duration noxious stimuli have led to the concept of preemptive analgesia. Ketorolac, a nonsteroidal anti-inflammatory drug, has been shown to have a postoperative narcotic-sparing effect when given preoperatively and alternatively to not have this effect. This study was undertaken to determine whether a single intravenous (IV) dose of ketorolac would result in decreased postoperative pain and narcotic requirements.

Methods

In a double-blind, randomized controlled trial, 48 women undergoing abdominal hysterectomy were studied. Patients in the ketorolac group received 30 mg of IV ketorolac 30 min before surgical incision, while the control group received normal saline. The postoperative analgesia was performed with a continuous infusi

SUBMITTER: Nistal-Nuno B 

PROVIDER: S-EPMC5389235 | biostudies-literature | 2017 Apr-Jun

REPOSITORIES: biostudies-literature