Effective amygdala-prefrontal connectivity predicts individual differences in successful emotion regulation.

ABSTRACT: The ability to voluntarily regulate our emotional response to threatening and highly arousing stimuli by using cognitive reappraisal strategies is essential for our mental and physical well-being. This might be achieved by prefrontal brain regions (e.g. inferior frontal gyrus, IFG) down-regulating activity in the amygdala. It is unknown, to which degree effective connectivity within the emotion-regulation network is linked to individual differences in reappraisal skills. Using psychophysiological interaction analyses of functional magnetic resonance imaging data, we examined changes in inter-regional connectivity between the amygdala and IFG with other brain regions during reappraisal of emotional responses and used emotion regulation success as an explicit regressor. During down-regulatio

SUBMITTER: Morawetz C 

PROVIDER: S-EPMC5390747 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature