Model selection with multiple regression on distance matrices leads to incorrect inferences.

ABSTRACT: In landscape genetics, model selection procedures based on Information Theoretic and Bayesian principles have been used with multiple regression on distance matrices (MRM) to test the relationship between multiple vectors of pairwise genetic, geographic, and environmental distance. Using Monte Carlo simulations, we examined the ability of model selection criteria based on Akaike's information criterion (AIC), its small-sample correction (AICc), and the Bayesian information criterion (BIC) to reliably rank candidate models when applied with MRM while varying the sample size. The results showed a serious problem: all three criteria exhibit a systematic bias toward selecting unnecessarily complex models containing spurious random variables and erroneously suggest a high level of support for t

SUBMITTER: Franckowiak RP 

PROVIDER: S-EPMC5390996 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature