Defining the next generation of Plasmodium vivax diagnostic tests for control and elimination: Target product profiles.

ABSTRACT: The global prevalence of malaria has decreased over the past fifteen years, but similar gains have not been realized against Plasmodium vivax because this species is less responsive to conventional malaria control interventions aimed principally at P. falciparum. Approximately half of all malaria cases outside of Africa are caused by P. vivax. This species places dormant forms in human liver that cause repeated clinical attacks without involving another mosquito bite. The diagnosis of acute patent P. vivax malaria relies primarily on light microscopy. Specific rapid diagnostic tests exist but typically perform relatively poorly compared to those for P. falciparum. Better diagnostic tests are needed for P. vivax. To guide their development, FIND, in collaboration with P. vivax experts, iden

SUBMITTER: Ding XC 

PROVIDER: S-EPMC5391123 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature