Influence of host factors and parasite biomass on the severity of imported Plasmodium falciparum malaria.

ABSTRACT:

Objectives

Imported malaria in France is characterized by various clinical manifestations observed in a heterogeneous population of patients such as travelers/expatriates and African migrants. In this population, host factors and parasite biomass associated with severe imported malaria are poorly known.

Methods

From data collected by the Centre National de Référence du Paludisme, we identified epidemiological, demographic and biological features including parasite biomass and anti-plasmodial antibody levels (negative, positive and strongly positive serology) associated with different disease severity groups (very severe, moderately severe, and uncomplicated malaria) in 3 epidemiological groups (travelers/expatriates, first- and second-generation migrants).

Results

Age

SUBMITTER: Argy N 

PROVIDER: S-EPMC5391917 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature