Addressing Common Questions Encountered in the Diagnosis and Management of Cardiac Amyloidosis.

ABSTRACT: Advances in cardiac imaging have resulted in greater recognition of cardiac amyloidosis in everyday clinical practice, but the diagnosis continues to be made in patients with late-stage disease, suggesting that more needs to be done to improve awareness of its clinical manifestations and the potential of therapeutic intervention to improve prognosis. Light chain cardiac amyloidosis, in particular, if recognized early and treated with targeted plasma cell therapy, can be managed very effectively. For patients with transthyretin amyloidosis, there are numerous therapies that are currently in late-phase clinical trials. In this review, we address common questions encountered in clinical practice regarding etiology, clinical presentation, diagnosis, and management of cardiac amyloidosis, focus

SUBMITTER: Maurer MS 

PROVIDER: S-EPMC5392416 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature