Massive donor transfusion potentially increases recipient mortality after lung transplantation.

ABSTRACT:

Objective

Donor blood transfusion has been identified as a potential risk factor for primary graft dysfunction and by extension early mortality. We sought to define the contributing risk of donor transfusion on early mortality for lung transplant.

Methods

Donor and recipient data were abstracted from the Organ Procurement and Transplantation Network database updated through June 30, 2014, which included 86,398 potential donors and 16,255 transplants. Using the United Network for Organ Sharing 4-level designation of transfusion (no blood, 1-5 units, 6-10 units, and >10 units, massive), we analyzed all-cause mortality at 30-days with the use of logistic regression adjusted for confounders (ischemic time, donor age, recipient diagnosis, lung allocation score and recipient age,

SUBMITTER: Borders CF 

PROVIDER: S-EPMC5392422 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature