Environmental Surveillance of Norovirus Genogroups I and II for Sensitive Detection of Epidemic Variants.

ABSTRACT: Sewage samples have been investigated to study the norovirus concentrations in sewage or the genotypes of noroviruses circulating in human populations. However, the statistical relationship between the concentration of the virus and the number of infected individuals and the clinical importance of genotypes or strains detected in sewage are unclear. In this study, we carried out both environmental and clinical surveillance of noroviruses for 3 years, 2013 to 2016. We performed cross-correlation analysis of the concentrations of norovirus GI or GII in sewage samples collected weekly and the reported number of gastroenteritis cases. Norovirus genotypes in sewage were also analyzed by pyrosequencing and compared with those identified in stool samples. The cross-correlation analysis found the

SUBMITTER: Kazama S 

PROVIDER: S-EPMC5394333 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature