The relationship between allergic status and adenotonsillar regrowth: a retrospective research on children after adenotonsillectomy.

ABSTRACT: Adenotonsillar regrowth in children after adenotonsillectomy (T&A) for obstructive sleep apnea (OSA) is often seen in clinical treatment, however, the relationship between allergic disease and adenotonsillar regrowth remains unclear. In this retrospective study, children were assigned to either the recurrence or control group, and subdivided by age at operation. Among children over 36 months, those in the recurrence group had more allergic disease and higher IgE, IL-4, and IL-5 levels than the same-aged children in control group. The Paediatric Allergic Disease Quality of Life Questionnaire (PADQLQ) scores for nasal symptoms and activity were higher in children older than 36 months in recurrence group. The results of immunohistochemistry and immunofluorescence showed that FoxP3+ cells (Tre

SUBMITTER: Huo Z 

PROVIDER: S-EPMC5394537 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature