Identification of growth trait related genes in a Yorkshire purebred pig population by genome-wide association studies.

ABSTRACT:

Objective

The aim of this study is to identify genomic regions or genes controlling growth traits in pigs.

Methods

Using a panel of 54,148 single nucleotide polymorphisms (SNPs), we performed a genome-wide Association (GWA) study in 562 pure Yorshire pigs with four growth traits: average daily gain from 30 kg to 100 kg or 115 kg, and days to 100 kg or 115 kg. Fixed and random model Circulating Probability Unification method was used to identify the associations between 54,148 SNPs and these four traits. SNP annotations were performed through the Sus scrofa data set from Ensembl. Bioinformatics analysis, including gene ontology analysis, pathway analysis and network analysis, was used to identify the candidate genes.

Results

We detected 6 significant and 12 sugg

SUBMITTER: Meng Q 

PROVIDER: S-EPMC5394831 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature