SSER: Species specific essential reactions database.

ABSTRACT:

Background

Essential reactions are vital components of cellular networks. They are the foundations of synthetic biology and are potential candidate targets for antimetabolic drug design. Especially if a single reaction is catalyzed by multiple enzymes, then inhibiting the reaction would be a better option than targeting the enzymes or the corresponding enzyme-encoding gene. The existing databases such as BRENDA, BiGG, KEGG, Bio-models, Biosilico, and many others offer useful and comprehensive information on biochemical reactions. But none of these databases especially focus on essential reactions. Therefore, building a centralized repository for this class of reactions would be of great value.

Description

Here, we present a species-specific essential reactions database (SSER

SUBMITTER: Labena AA 

PROVIDER: S-EPMC5395902 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature