Induction of labour with retrievable prostaglandin vaginal inserts: outcomes following retrieval due to an intrapartum adverse event.

ABSTRACT:

Objective

To assess adverse event (AE) resolution, delivery mode and neonatal outcomes after misoprostol or dinoprostone vaginal insert (MVI or DVI) retrieval due to AE during induction of labour (IOL).

Design

Randomised, double-blind trial, EXPEDITE.

Setting

Thirty five obstetric departments, USA.

Population

Consisted of 1358 pregnant women with modified Bishop score ≤4 eligible for pharmacological IOL.

Methods

Post hoc analysis.

Main outcome measures

AEs prompting insert retrieval, times to AE resolution, delivery, delivery mode and neonatal intensive care unit (NICU) admissions.

Results

77/678 (11.4%) and 27/680 (4.0%) women had MVI and DVI retrieved due to AE, respectively (P < 0.001). The most common AEs prompting retrieval were uterin

SUBMITTER: Rugarn O 

PROVIDER: S-EPMC5396314 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature