Risk of Herpes Zoster in Autoimmune and Inflammatory Diseases: Implications for Vaccination.

ABSTRACT:

Objective

The herpes zoster (HZ) vaccine is recommended for adults in the US ages ≥60 years who do not have weakened immune systems. It is unclear how the risk of HZ varies according to age and disease conditions in younger patients with autoimmune or inflammatory (AI) diseases. This study was undertaken to evaluate the age-stratified incidence of HZ in patients with AI diseases as compared to older adults for whom the HZ vaccine is currently recommended by the US Centers for Disease Control and Prevention.

Methods

Using linked data obtained from patients who were insured by US commercial and government health care plans during the period 2007-2010, 7 cohorts of patients with AI diseases were assembled: systemic lupus erythematosus (SLE), inflammatory bowel disease (IBD), rh

SUBMITTER: Yun H 

PROVIDER: S-EPMC5396838 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature