HacDivSel: Two new methods (haplotype-based and outlier-based) for the detection of divergent selection in pairs of populations.

ABSTRACT: The detection of genomic regions involved in local adaptation is an important topic in current population genetics. There are several detection strategies available depending on the kind of genetic and demographic information at hand. A common drawback is the high risk of false positives. In this study we introduce two complementary methods for the detection of divergent selection from populations connected by migration. Both methods have been developed with the aim of being robust to false positives. The first method combines haplotype information with inter-population differentiation (FST). Evidence of divergent selection is concluded only when both the haplotype pattern and the FST value support it. The second method is developed for independently segregating markers i.e. there is no ha

SUBMITTER: Carvajal-Rodriguez A 

PROVIDER: S-EPMC5397020 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature