Pathologic correlates of supranuclear gaze palsy with parkinsonism.

ABSTRACT:

Introduction

Supranuclear gaze palsy (SGP) is a classic clinical feature of progressive supranuclear palsy (PSP) but is not specific for this diagnosis and has been reported to occur in several other neurodegenerative parkinsonian conditions. Our objective was to evaluate the association between SGP and autopsy-proven diagnoses in a large population of patients with parkinsonism referred to a tertiary movement disorders clinic.

Methods

We reviewed clinical and autopsy data maintained in an electronic medical record from all patients seen in the Movement Disorders Clinic at Washington University, St. Louis between 1996 and 2015. All patients with parkinsonism from this population who had subsequent autopsy confirmation of diagnosis underwent further analysis.

Results

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SUBMITTER: Martin WRW 

PROVIDER: S-EPMC5397329 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature