Experimental design data for the biosynthesis of citric acid using Central Composite Design method.

ABSTRACT: In the present investigation, we report that statistical design and optimization of significant variables for the microbial production of citric acid from sucrose in presence of filamentous fungi A. niger NCIM 705. Various combinations of experiments were designed with Central Composite Design (CCD) of Response Surface Methodology (RSM) for the production of citric acid as a function of six variables. The variables are; initial sucrose concentration, initial pH of medium, fermentation temperature, incubation time, stirrer rotational speed, and oxygen flow rate. From experimental data, a statistical model for this process has been developed. The optimum conditions reported in the present article are initial concentration of sucrose of 163.6 g/L, initial pH of medium 5.26, stirrer rot

SUBMITTER: Kola AK 

PROVIDER: S-EPMC5397574 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature