Cerebrovascular Manifestations of Lyme Neuroborreliosis-A Systematic Review of Published Cases.

ABSTRACT:

Background

Lyme neuroborreliosis (LNB) is a disease caused by spirochete Borrelia burgdorferi, involving the nervous system. It usually manifests as lymphocytic meningoradiculitis, but in rare cases, it can also lead to cerebrovascular complications. We aimed to perform a systematic review of all reported cases of LNB complicated by central nervous system vasculitis and stroke or transient ischemic attack (TIA).

Materials and methods

We conducted a systematic review of literature between May 1987 and December 2016 with patients who presented with cerebrovascular course of LNB.

Results

This study included 88 patients with a median age of 46 years. The median interval from onset of symptoms suggesting Lyme disease to first symptoms of cerebrovascular manifestatio

SUBMITTER: Garkowski A 

PROVIDER: S-EPMC5397664 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature