Analysis of transcriptome data reveals multifactor constraint on codon usage in Taenia multiceps.

ABSTRACT:

Background

Codon usage bias (CUB) is an important evolutionary feature in genomes that has been widely observed in many organisms. However, the synonymous codon usage pattern in the genome of T. multiceps remains to be clarified. In this study, we analyzed the codon usage of T. multiceps based on the transcriptome data to reveal the constraint factors and to gain an improved understanding of the mechanisms that shape synonymous CUB.

Results

Analysis of a total of 8,620 annotated mRNA sequences from T. multiceps indicated only a weak codon bias, with mean GC and GC3 content values of 49.29% and 51.43%, respectively. Our analysis indicated that nucleotide composition, mutational pressure, natural selection, gene expression level, amino acids with grand average of hydropathicit

SUBMITTER: Huang X 

PROVIDER: S-EPMC5397707 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature