Benign metastasizing leiomyoma: A review of current literature in respect to the time and type of previous gynecological surgery.

ABSTRACT:

Introduction

Benign metastasizing leiomyoma (BML) is a rare disorder that affects women with a history of uterine leiomyoma, which is found to metastasise within extrauterine sites. The aetiology of BML remains unexplained. Because BML is rare, and most publications contain descriptions of single cases, no statistically determined time relations were found between the primary and secondary surgeries, which may have aetiological implications.

Objectives

To determine age before BML surgery, age during diagnosis of BML, type of prior surgery, and location of metastasis based on the literature.

Methods

A systematic review of four databases (Medline/PubMed, Embase, Web of Science, and Cochrane) covering articles published from 1 January 1965 to 10 April 2016. The inclusion

SUBMITTER: Barnas E 

PROVIDER: S-EPMC5398563 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature