Early application of tail nerve electrical stimulation-induced walking training promotes locomotor recovery in rats with spinal cord injury.

ABSTRACT:

Study design

This is a randomized controlled prospective trial with two parallel groups.

Objectives

The objective of this study was to determine whether early application of tail nerve electrical stimulation (TANES)-induced walking training can improve the locomotor function.

Setting

This study was conducted in SCS Research Center in Colorado, USA.

Methods

A contusion injury to spinal cord T10 was produced using the New York University impactor device with a 25 -mm height setting in female, adult Long-Evans rats. Injured rats were randomly divided into two groups (n=12 per group). One group was subjected to TANES-induced walking training 2 weeks post injury, and the other group, as control, received no TANES-induced walking training. Restorations of behavior an

SUBMITTER: Zhang SX 

PROVIDER: S-EPMC5399155 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature