Statin use and mortality in rheumatoid arthritis: a general population-based cohort study.

ABSTRACT:

Background

Dual lipid-lowering and anti-inflammatory properties of statins may lead to survival benefits in patients with rheumatoid arthritis (RA). However, data on this topic are limited, and the role of statins in RA remains unclear.

Objectives

To examine the association of statin use with overall mortality among patients with RA in a general population context.

Methods

We conducted an incident user cohort study with time-stratified propensity score matching using a UK general population database. The study population included individuals aged ≥20 years who had a diagnosis of RA and had used at least one disease-modifying antirheumatic drug (DMARD) between January 2000 and December 2012. To closely account for potential confounders, we compared propensity score mat

SUBMITTER: Schoenfeld SR 

PROVIDER: S-EPMC5399680 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature