Vancomycin-modified Fe₃O₄@SiO₂@Ag microflowers as effective antimicrobial agents.

ABSTRACT: Nanomaterials combined with antibiotics exhibit synergistic effects and have gained increasing interest as promising antimicrobial agents. In this study, vancomycin-modified magnetic-based silver microflowers (Van/Fe₃O₄@SiO₂@Ag microflowers) were rationally designed and prepared to achieve strong bactericidal ability, a wide antimicrobial spectrum, and good recyclability. High-performance Fe₃O₄@SiO₂@Ag microflowers served as a multifunction-supporting matrix and exhibited sufficient magnetic response property due to their 200 nm Fe₃O₄ core. The microflowers also possessed a highly branched flower-like Ag shell that provided a large surface area for effective Ag ion release and bacterial contact. The mod

SUBMITTER: Wang C 

PROVIDER: S-EPMC5399987 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature