Assessment of the significance of patent-derived information for the early identification of compound-target interaction hypotheses.

ABSTRACT:

Background

Patents are an important source of information for effective decision making in drug discovery. Encouragingly, freely accessible patent-chemistry databases are now in the public domain. However, at present there is still a wide gap between relatively low coverage-high quality manually-curated data sources and high coverage data sources that use text mining and automated extraction of chemical structures. To secure much needed funding for further research and an improved infrastructure, hard evidence is required to demonstrate the significance of patent-derived information in drug discovery. Surprisingly little such evidence has been reported so far. To address this, the present study attempts to quantify the relevance of patents for formulating and substantiating hypothe

SUBMITTER: Senger S 

PROVIDER: S-EPMC5400772 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature