Management and outcomes of severe dengue patients presenting with sepsis in a tropical country.

ABSTRACT:

Background

Dengue is a common cause of infection in adults in tropical countries. Sepsis is a syndrome of systemic manifestations induced by infection of any organisms; including bacterial, fungal and viral agents. Here, we investigated the diagnosis, management and outcomes of dengue patients presenting with sepsis in a prospective study of community-acquired sepsis in Thailand.

Methods

From June to December 2015, 874 adult patients (age≥18 years) with suspected or documented community-acquired infection, with ≥3 diagnostic criteria for sepsis according to the Surviving Sepsis Campaign 2012, and within 24 hours of admission were evaluated. Serum was stored and later tested for dengue PCR assays.

Results

A total of 126 patients had dengue PCR assays positive (2 DENV-1

SUBMITTER: Teparrukkul P 

PROVIDER: S-EPMC5402971 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature