Optical resonance imaging: An optical analog to MRI with sub-diffraction-limited capabilities.

ABSTRACT: We propose here optical resonance imaging (ORI), a direct optical analog to magnetic resonance imaging (MRI). The proposed pulse sequence for ORI maps space to time and recovers an image from a heterodyne-detected third-order nonlinear photon echo measurement. As opposed to traditional photon echo measurements, the third pulse in the ORI pulse sequence has significant pulse-front tilt that acts as a temporal gradient. This gradient couples space to time by stimulating the emission of a photon echo signal from different lateral spatial locations of a sample at different times, providing a widefield ultrafast microscopy. We circumvent the diffraction limit of the optics by mapping the lateral spatial coordinate of the sample with the emission time of the signal, which can be measured to high

SUBMITTER: Allodi MA 

PROVIDER: S-EPMC5403159 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature