Visuospatial executive function in Turner syndrome: functional MRI and neurocognitive findings.

ABSTRACT: Turner syndrome is a genetic disorder that results from an abnormal or missing X chromosome in females and is typically associated with impairments in visuospatial, but not verbal, information processing. These visuospatial processing impairments may be exacerbated with increased task demands, such as those engaged during working memory (WM). While previous studies have examined spatial WM function in Turner syndrome, none have directly compared the neural correlates of spatial and verbal WM processes across the encoding, maintenance and retrieval phases. We employed both neurocognitive assessments and functional MRI (fMRI) to examine the neural circuitry underlying both verbal and visuospatial WM functions in individuals with Turner syndrome and normal controls. We furthermore examined th

SUBMITTER: Hart SJ 

PROVIDER: S-EPMC5403411 | biostudies-literature | 2006 May

REPOSITORIES: biostudies-literature