An auditory display tool for DNA sequence analysis.

ABSTRACT:

Background

DNA Sonification refers to the use of an auditory display to convey the information content of DNA sequence data. Six sonification algorithms are presented that each produce an auditory display. These algorithms are logically designed from the simple through to the more complex. Three of these parse individual nucleotides, nucleotide pairs or codons into musical notes to give rise to 4, 16 or 64 notes, respectively. Codons may also be parsed degenerately into 20 notes with respect to the genetic code. Lastly nucleotide pairs can be parsed as two separate frames or codons can be parsed as three reading frames giving rise to multiple streams of audio.

Results

The most informative sonification algorithm reads the DNA sequence as codons in three reading frames to prod

SUBMITTER: Temple MD 

PROVIDER: S-EPMC5404335 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature