Comparison of the Efficacy and Safety of Early Rule-Out Pathways for Acute Myocardial Infarction.

ABSTRACT:

Background

High-sensitivity cardiac troponin assays enable myocardial infarction to be ruled out earlier, but the optimal approach is uncertain. We compared the European Society of Cardiology rule-out pathway with a pathway that incorporates lower cardiac troponin concentrations to risk stratify patients.

Methods

Patients with suspected acute coronary syndrome (n=1218) underwent high-sensitivity cardiac troponin I measurement at presentation and 3 and 6 or 12 hours. We compared the European Society of Cardiology pathway (<99th centile at presentation or at 3 hours if symptoms <6 hours) with a pathway developed in the High-STEACS study (High-Sensitivity Troponin in the Evaluation of Patients With Acute Coronary Syndrome) population (<5 ng/L at presentation or change <3

SUBMITTER: Chapman AR 

PROVIDER: S-EPMC5404406 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature