Tumor response assessment by MRI following stereotactic body radiation therapy for hepatocellular carcinoma.

ABSTRACT:

Background

To evaluate the MRI features of a tumor response, local control, and predictive factors of local control after stereotactic body radiation therapy (SBRT) for hepatocellular carcinoma (HCC).

Methods

Thirty-five consecutive patients with 48 HCCs who were treated by SBRT were included in this retrospective study. All patients provided written informed consent to be treated by SBRT, and prior to inclusion they authorized use of the treatment data for further studies. The assessment was made using MRI, with determination of local and hepatic responses according to Response Evaluation Criteria in Solid Tumors (RECIST) and modified RECIST (mRECIST) criteria during a two-year follow-up.

Results

The local response rate according to mRECIST was higher than with RECIS

SUBMITTER: Oldrini G 

PROVIDER: S-EPMC5404860 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature