Esophageal Cancer: Associations With (pN+) Lymph Node Metastases.

ABSTRACT:

Objectives

To identify the associations of lymph node metastases (pN+), number of positive nodes, and pN subclassification with cancer, treatment, patient, geographic, and institutional variables, and to recommend extent of lymphadenectomy needed to accurately detect pN+ for esophageal cancer.

Summary background data

Limited data and traditional analytic techniques have precluded identifying intricate associations of pN+ with other cancer, treatment, and patient characteristics.

Methods

Data on 5806 esophagectomy patients from the Worldwide Esophageal Cancer Collaboration were analyzed by Random Forest machine learning techniques.

Results

pN+, number of positive nodes, and pN subclassification were associated with increasing depth of cancer invasion (pT), incre

SUBMITTER: Rice TW 

PROVIDER: S-EPMC5405457 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature